9oeg

Structure of the human astrovirus VA1 capsid spike bound to antibody 2A2

spinqualitylabelsall models 9oeg, resolution 3.05Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 9oeg is a 6 chain structure with sequence from Astrovirus VA1 and Mus musculus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 3.05Å Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function CAPSD_HASVA The capsid polyprotein VP90 self-assembles and undergoes a proteolytic cleavage by host caspases to yield the immature VP70 virion.[UniProtKB:Q9IFX1] Self-assembles to form an icosahedral capsid with a T=3 symmetry, about 43 nm in diameter.[UniProtKB:O12792] Forms the spikes at the surface of the virion (PubMed:38416796). Plays a role in the attachment to target host cell (By similarity).[UniProtKB:O12792]

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