9ppu

Beta-sandwich forming metallopeptide

spinqualitylabelsall models 9ppu, resolution 1.49Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 9ppu is a 2 chain structure with sequence from Synthetic construct. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.49Å Ligands: ACA, CU, FMT, ORN Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Publication Abstract from PubMed The active site of multicopper oxidases contains three Cu ions coordinated to a beta-sandwich motif. Here, we designed a small peptide ligand that closely mimics the beta-sandwich. We verified the sandwich architecture by X-ray crystallography, showing its high resemblance to the active site and ability to coordinate two Cu(II) ions. A bis-macrocylic peptide ligand mimicking the beta-sandwich active site of multicopper oxidases.,Dang VT, Drena A, Telser J, Wofford L, Nguyen AI Dalton Trans. 2026 Apr 21;55(15):5877-5881. doi: 10.1039/d6dt00494f. PMID:41969027 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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