Structural highlights
9sij is a 1 chain structure with sequence from Salmonella phage epsilon15. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Method: | X-ray diffraction, Resolution 1.643Å |
| Ligands: | EDO, FLC, GOL, MSE, PEG, PG4 |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Function
FIBER_BPE15 Structural component of the short non-contractile tail (PubMed:16452981). The tail comprises six spikes that mediate primary attachment to the host cell lipopolysaccharides (LPS) and display endorhamnosidase enzymatic activity, hydrolyzing the linkage between rhamnose and galactose of the O-antigen polysaccharide. Digestion of the LPS brings the capsid near the cell outer membrane (PubMed:20709082, PubMed:4633001).[1] [2] [3]
References
- ↑ Jiang W, Chang J, Jakana J, Weigele P, King J, Chiu W. Structure of epsilon15 bacteriophage reveals genome organization and DNA packaging/injection apparatus. Nature. 2006 Feb 2;439(7076):612-6. doi: 10.1038/nature04487. PMID:16452981 doi:https://dx.doi.org/10.1038/nature04487
- ↑ Chang JT, Schmid MF, Haase-Pettingell C, Weigele PR, King JA, Chiu W. Visualizing the structural changes of bacteriophage Epsilon15 and its Salmonella host during infection. J Mol Biol. 2010 Oct 1;402(4):731-40. doi: 10.1016/j.jmb.2010.07.058. Epub 2010 , Aug 13. PMID:20709082 doi:https://dx.doi.org/10.1016/j.jmb.2010.07.058
- ↑ PMID: https://pubmed.ncbi.nlm.nih.gov/4633001/
