9t3x
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cryo-EM strucutre of CPSF160-WDR33-ZC3H18
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Structural highlights
FunctionCPSF1_HUMAN Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction.[1] References
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This page was last modified 14:44, 10 February 2026.