9u3p

Cryo-EM structure of human AC9-Gs complex (soluble domain)

spinqualitylabelsall models 9u3p, resolution 2.65Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 9u3p is a 2 chain structure with sequence from Homo sapiens and Human orthopneumovirus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 2.65Å Ligands: GSP, MG Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function ADCY9_HUMAN Adenylyl cyclase that catalyzes the formation of the signaling molecule cAMP in response to activation of G protein-coupled receptors (PubMed:10987815, PubMed:12972952, PubMed:15879435, PubMed:9628827). Contributes to signaling cascades activated by CRH (corticotropin-releasing factor), corticosteroids and beta-adrenergic receptors (PubMed:9628827).

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