9udx
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Cryo-EM structure of the human G6P transporter SLC37A2 in the presence of G6P with a symmetric ER luminal-open conformation.
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Structural highlights
FunctionG6PT3_HUMAN Inorganic phosphate and glucose-6-phosphate antiporter. May transport cytoplasmic glucose-6-phosphate into the lumen of the endoplasmic reticulum and translocate inorganic phosphate into the opposite direction. Independent of a lumenal glucose-6-phosphatase. May not play a role in homeostatic regulation of blood glucose levels.[1] References
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This page was last modified 09:44, 6 November 2025.