Structural highlights
9vbx is a 4 chain structure with sequence from Lablab purpureus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
|
| Method: | Electron Microscopy, Resolution 2.4Å |
| Ligands: | CA, FUC, GAL, MAN, MN, NAG |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Function
FRIL_LABPU Mannose-binding lectin (PubMed:9892687). Accommodates most effectively a non-reducing terminal alpha-d-mannosyl unit. Strongly precipitates murine IgM but not IgG (PubMed:9949194).[1] [2]
References
- ↑ Colucci G, Moore JG, Feldman M, Chrispeels MJ. cDNA cloning of FRIL, a lectin from Dolichos lablab, that preserves hematopoietic progenitors in suspension culture. Proc Natl Acad Sci U S A. 1999 Jan 19;96(2):646-50. PMID:9892687 doi:10.1073/pnas.96.2.646
- ↑ Mo H, Meah Y, Moore JG, Goldstein IJ. Purification and characterization of Dolichos lablab lectin. Glycobiology. 1999 Feb;9(2):173-9. PMID:9949194
