9vm7

Structure of DOCK6 tetramer complexed with Rac1

spinqualitylabelsall models 9vm7, resolution 6.85Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 9vm7 is a 8 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 6.85Å Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease DOCK6_HUMAN Adams-Oliver syndrome. The disease is caused by variants affecting the gene represented in this entry. Function DOCK6_HUMAN Acts as a guanine nucleotide exchange factor (GEF) for CDC42 and RAC1 small GTPases. Through its activation of CDC42 and RAC1, may regulate neurite outgrowth (By similarity).

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