9w0l

S1P3 in complex with CYM52581 and spm242

spinqualitylabelsall models 9w0l, resolution 3.60Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 9w0l is a 1 chain structure with sequence from Homo sapiens and Niallia circulans. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 3.6Å Ligands: A1EUC, A1EUD Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function XYNA_NIACI S1PR3_HUMAN Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis.

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