9wda

Paclitaxel/GMPCPP-stabilized human alpha1A/beta3 microtubule

spinqualitylabelsall models 9wda, resolution 2.35Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 9wda is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 2.35Å Ligands: G2P, GTP, MG, TA1 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease TBA1A_HUMAN Lissencephaly due to TUBA1A mutation. The disease is caused by mutations affecting the gene represented in this entry. Function TBA1A_HUMAN Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.

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