Structural highlights
Function
AB2C_ARATH Pump for glutathione S-conjugates. Mediates the transport of S-conjugates such as GSH, S-(2,4-dinitrophenyl)-glutathione (DNP-GS), GSSG, cyanidin 3-glucoside-GS (C3G-GS) and metolachlor-GS (MOC-GS), glucuronides such as 17-beta-estradiol 17-(beta-D-glucuronide) (E(2)17betaG), and of the chlorophyll catabolite such as B.napus nonfluorescent chlorophyll catabolite (Bn-NCC-1).[1] [2]
References
- ↑ Liu G, Sánchez-Fernández R, Li ZS, Rea PA. Enhanced multispecificity of arabidopsis vacuolar multidrug resistance-associated protein-type ATP-binding cassette transporter, AtMRP2. J Biol Chem. 2001 Mar 23;276(12):8648-56. PMID:11115509 doi:10.1074/jbc.M009690200
- ↑ Lu YP, Li ZS, Drozdowicz YM, Hortensteiner S, Martinoia E, Rea PA. AtMRP2, an Arabidopsis ATP binding cassette transporter able to transport glutathione S-conjugates and chlorophyll catabolites: functional comparisons with Atmrp1. Plant Cell. 1998 Feb;10(2):267-82. PMID:9490749 doi:10.1105/tpc.10.2.267
