9wks

Crystal structure of hen egg-white lysozyme determined in the commissioning of NanoTerasu MX-ES

spinqualitylabelsall models 9wks, resolution 1.20Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 9wks is a 1 chain structure with sequence from Gallus gallus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.2Å Ligands: CL, NA Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function LYSC_CHICK Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus. Publication Abstract from PubMed Since the fiscal year 2022, ;Support Program for Life Science and Drug Discovery Research (BINDS Phase II)', funded by the Japan Agency for Medical Research and Development (AMED), has been supporting structural analysis research in Japan, promoting the further development of various advanced structural analysis technologies. The BINDS project aims to offer more timely and cutting-edge support by establishing a new macromolecular crystallography endstation (MX-ES) at NanoTerasu, Japan's first fourth-generation synchrotron-radiation facility. MX-ES has been equipped with microbeam focusing optics and a state-of-the-art measurement system for fully automated, high-throughput data collection from cooled crystals. Commissioning and initial experiments have been completed. User operations are expected to begin in the second half of the fiscal year 2025. A new macromolecular crystallography endstation at NanoTerasu for accelerating structural biology and drug discovery.,Yamada Y, Sakurai K, Fukuda A, Yamane H, Hatano T, Nakamura T, Ueno G, Masunaga T, Yamamoto M, Nango E Acta Crystallogr D Struct Biol. 2026 Jan 1;82(Pt 1):23-29. doi: , 10.1107/S2059798325011234. Epub 2026 Jan 1. PMID:41420545 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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