9x02 | pdb_00009x02

Crystal structure of human type VII collagen vWFA2 domain in complex with homo-trimeric collagen model peptide.

spinqualitylabelsall models 9x02, resolution 1.47Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 9x02 is a 8 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.47Å Ligands: ACE, HYP, KLF, NLE, SO4 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease CO7A1_HUMAN Self-improving dystrophic epidermolysis bullosa;Localized dystrophic epidermolysis bullosa, nails only;Autosomal recessive generalized dystrophic epidermolysis bullosa, intermediate form;Localized dystrophic epidermolysis bullosa, pretibial form;Autosomal dominant generalized dystrophic epidermolysis bullosa;Localized dystrophic epidermolysis bullosa, acral form;Dystrophic epidermolysis bullosa pruriginosa;Autosomal recessive generalized dystrophic epidermolysis bullosa, severe form;Recessive dystrophic epidermolysis bullosa inversa. Epidermolysis bullosa acquisita (EBA) is an autoimmune acquired blistering skin disease resulting from autoantibodies to type VII collagen. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. Function CO7A1_HUMAN Stratified squamous epithelial basement membrane protein that forms anchoring fibrils which may contribute to epithelial basement membrane organization and adherence by interacting with extracellular matrix (ECM) proteins such as type IV collagen.

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