9y93

Tetrameric InvE from Salmonella Typhimurium

spinqualitylabelsall models 9y93, resolution 2.42Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 9y93 is a 4 chain structure with sequence from Salmonella enterica subsp. enterica serovar Typhimurium. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 2.42Å Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function INVE_SALTY Involved in the triggering of intracellular events that lead to microbial internalization. These events include increase in calcium level, redistribution of actin microfilaments, and changes in the normal structure of the microvilli. Encoded within the type III secretion system (SPI-1 T3SS), it is essential for the translocation of protein effectors into host cells. Forms a complex with SipB and SipC in the presence of their chaperone SicA. Positively regulates the secretion of SPI-1 T3SS effector proteins SipB, SipC and SipD and negatively influences the secretion of SipA, SopA and SptP.

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