9yp4

Cryo-EM structure of human beta-cardiac myosin bound to omecamtiv mecarbil in the interacting-heads motif and S2-FH docked state

spinqualitylabelsall models 9yp4, resolution 4.50Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 9yp4 is a 6 chain structure with sequence from Aequorea victoria, Homo sapiens, Mus musculus and Saccharomyces cerevisiae. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 4.5Å Ligands: 2OW, ADP, PO4 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function MYL11_MOUSE Myosin regulatory subunit that plays an essential role to maintain muscle integrity during early development (PubMed:17356007). Plays a role in regulation of muscle contraction (By similarity).[UniProtKB:O93409]

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