Structural highlights
Function
PIC_ECO44 Involved in intestinal colonization, displays in vitro mucinolytic activity, serum resistance, and hemagglutination. Important to penetrate the intestinal mucus layer.[1]
References
- ↑ Henderson IR, Czeczulin J, Eslava C, Noriega F, Nataro JP. Characterization of pic, a secreted protease of Shigella flexneri and enteroaggregative Escherichia coli. Infect Immun. 1999 Nov;67(11):5587-96. doi: 10.1128/IAI.67.11.5587-5596.1999. PMID:10531204 doi:https://dx.doi.org/10.1128/IAI.67.11.5587-5596.1999