A1YIY3 9GAMM

spinqualitylabelsall models Fragment of beta-helical antifreeze protein complex with Ca+2 ions (green) and acetate (PDB code 3p4g) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D

The ice formation of water (red spheres) being scrambled (blue spheres) by the protein

Threonines and Aspartates are lined up in a manner that binds nearby water molecules in a manner that is off-set from the ice crystal lattice

Marinomonas primoryensis

Isolated from marine coastal sea-ice. Marinomonas primoryensis is aerobic, Gram-negative, psychrophilic, halophilic and motile by means of a single polar flagellum. This bacteria survives in extreme cold and high salinity environments.

Structural highlights

The distinct beta-sheet roll in this ice binding protein is stabilized by a series of Calcium ions. This beta sheet roll sets up in a row several amino acids capable of forming a hydrogen bond with water creating a Ice-Binding Site

References

Garnham, Christopher P., Robert L. Campbell, and Peter L. Davies. "Anchored clathrate waters bind antifreeze proteins to ice." Proceedings of the National Academy of Sciences 108.18 (2011): 7363-7367.

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