ATP-dependent Clp protease adaptor protein

spinqualitylabelsall models E. coli ClpS (deep sky blue) complex with peptide (green) (PDB code 3o2h) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Function ATP-dependent Clp protease adaptor protein (ClpS) influences the protein degradation by binding to the chaperone-protease ClpAP toward degradation of aggregated proteins. Degradation susceptibility is related to N-terminal residues. It is formulated by the N-end rule. In bacteria the residues are Tyr, Phe, Trp and Leu. ClpS binds these residues and delivers the protein to degradation by ClpAP. Structural highlights ClpS His residue binds to the N-terminal Leu which is one of the N-end rule residues. 3D Structures of ATP-dependent Clp protease adaptor protein ATP-dependent Clp protease adaptor protein 3D structures

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman