Beta-2 microglobulin

spinqualitylabelsall models Humanβ-2 microglobulin (green) complex with MHC I (magenta) and HCMV PP65 nonapeptide (cyan), 3mrb Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Beta-2 microglobulin (B2M) is a component of MHC class I system. B2M associates with MHC class I α chain, CD1 and Qa. Loss of B2M function causes iron excess. For more details, see: Human beta two microglobulin and Molecular playground/beta 2 microglobulin. Diagram of MHC I Complex Disease Elevated B2M levels are found in patients of liver cirrhosis and hepatitis. Dialysis-associated amyloidosis is a serious complication in chronic dialysis patients. It is caused by B2M fibrils amyloid deposits. Relevance B2M is used as a marker for certain types of blood cell cancer. It can indicate the spread and severity of myeloma. Structural Highlights Human β-2 microglobulin with MHC class I HLA-A2 and HCMV PP65 nonapeptide (3mrb). 3D Structures of β-2 microglobulin Beta-2 microglobulin 3D structures

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