Dipeptidyl peptidase 3D structures

3D Structures of Dipeptidyl peptidase

Updated on 14-April-2025

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• DPP-I see Cathepsin C.
• DPP-II
  • 3n0t – hDPP-II peptidase domain residues 28-492+inhibitor
    
  • 3jyh, 4ebb – hDPP-II peptidase domain residues 28-492
    
• DPP-III
  • 3fvy, 5egy – hDPP-III
    
  • 3t6b, 3t6j - hDPP-III (mutant) + tynorphin
    
  • 5e2q - hDPP-III (mutant) + angiotensin II
    
  • 5e33, 5e3a - hDPP-III (mutant) + enkephalin
    
  • 5e3c - hDPP-III (mutant) + opioid peptide
    
  • 5ehh - hDPP-III (mutant) + endomorphin II
    
  • 7oup - hDPP-III (mutant) + peptidomimetic
    
  • 3csk – DPP-III (mutant) – yeast
    
  • 5yfb, 5yfc, 5yfd – DPP-III – mushroom
    
  • 5zum - DPP-III - Corallococcus
    
  • 5na7, 5na8 – BtDPP-III – Bacterioides thetaiotamicron
    
  • 5na6 - BtDPP-III (mutant)
    
• DPP-IV (CD26)
  • 1j2e, 1nu6, 1pfq, 1r9m, 1tk3, 2onc – hDPP-IV extracellular domain
    
  • 1u8e – hDPP-IV extracellular domain (mutant)
    
  • 3kwj, 3kwf, 3oc0, 3q8w – hDPP-IV extracellular domain +quinoline derivative
    
  • 1n1m, 1rwq, 1tkr, 1wcy, 2ajl, 2bub, 2g5p, 2g5t, 2g63, 2i03, 2i78, 2jid, 2oag, 2ogz, 2ole, 2oqi, 2oqv, 2qjr, 2qky, 2rgu, 2rip, 3bjm, 3ccb, 3ccc, 3d4l, 3eio, 3g0b, 3f8s, 3g0c, 3g0d, 3g0g, 3h0c, 3hab, 3hac, 3nox, 3o95, 3o9v, 3opm, 3q0t, 3sww, 3sx4, 3vjk, 3vjl, 3vjm, 3w2t, 3wqh, 4a5s, 4dsa, 4dsz, 4dtc, 4g1f, 4j3j, 4jh0, 4lko, 4n8d, 4n8e, 4pnz, 4pv7, 5i7u, 5j3j, 5kby, 5t4b, 5t4e, 5t4f, 5t4h, 5y7k, 5y7j, 5y7h, 5zid – hDPP-IV extracellular domain+inhibitor
    
  • 6b1e, 6b1o – hDPP-IV extracellular domain (mutant) +inhibitor
    
  • 1nu8, 1r9n, 2bgr – hDPP-IV extracellular domain+polypeptide
    
  • 1w1i – hDPP-IV extracellular domain+adenosine deaminase
    
  • 2bgn – hDPP-IV extracellular domain+adenosine deaminase+polypeptide
    
  • 1x70, 2fjp, 2iit, 2iiv, 2oph, 2p8s, 2qoe, 2qt9, 2qtb, 3c43, 3c45, 3qbj, 5ism – hDPP-IV extracellular domain (mutant) + inhibitor
    
  • 4kr0, 4qzv - hDPP-IV extracellular domain + S protein
    
  • 8wku, 8zdx – hDPP-IV + pangolin Cov Rbd
    
  • 1orw, 2aj8, 2ajb, 2ajc, 2ajd, 2bua, 2buc, 5lls, 7xnm – pDPP-IV extracellular domain+inhibitor - pig
    
  • 1orv - pDPP-IV extracellular domain
    
  • 4l72 – rDPP-IV + Mers-Cov Rbd
    
  • 2gbc – rDPP-IV extracellular domain
    
  • 2gbf, 2gbg, 2gbi, 2i3c, ]]2oae]] – rDPP-IV extracellular domain+inhibitor
    
  • 4ffv, 4ffw, 5vta – rDPP-IV + antibody
    
  • 8ze6 – DPP-IV + Cov Rbd – pangolin
    
  • 6l8q – DPP-IV + Mers-Cov Rbd - bat
    
  • 8pba - DPP-IV – Caenoharbditis elegansCryo EM
    
  • 2ecf - SmDPP-IV – Stenotrophomonas maltophilia
    
  • 5olj – PgDPP-IV – Porphyromonas gingivalis
    
  • 5yp1 – PmDPP-IV – Pseudomonas mexicana
    
  • 5yp3, 5yp4 – PmDPP-IV + dipeptide
    
  • 7y4f - BtDPP-IV
    
• DPP-VI or dipeptidyl aminopeptidase-like protein 6
  • 7e89, 7e8g – hDPP-VI extracellular domain 121-849 – Cryo EM
    
  • 7e8b, 7ukg – hDPP-VI extracellular domain + Kv4.2 – Cryo EM
    
  • 7e8h – hDPP-VI extracellular domain + Kv4.2 + KCHIP1 – Cryo EM
    
  • 7e87 – hDPP-VI 94-120 + Kv4.2 – Cryo EM
    
  • 7e8e – hDPP-VI 94-120 + Kv4.2 + KCHIP1 – Cryo EM
    
  • 3pvq, 4r0k – BtDPP-VI
• DPP-VII
  • 8grt – SmDPP-VII
    
  • 7dkb – SmDPP-VII + inhibitor
    
  • 7dkd, 7dke – SmDPP-VII + dipeptide
    
• DPP-VIII
  • 6eoo, 6eos – hDPP-VIII
    
  • 6eop, 6eot, 6qzw, 6trw – hDPP-VIII + polypeptide
    
  • 6hp8, 7svm – hDPP-VIII + pyrrolidine derivative
    
  • 6trx, 7a3g, 7a3i, 7a3j, 7a3k, 7a3l, 7ayq, 7ayr, 7or4, 7oz7 – hDPP-VIII + inhibitor
    
• DPP-IX
  • 6eoq, 6eor, 7a3f – hDPP-IX
    
  • 6qzv – hDPP-IX + dipeptide
    
  • 7svl, 7svn, 7svo, 7zxs – hDPP-IX + inhibitor
    
  • 7jkq, 7jn7 – hDPP-IX + CARD8 – Cryo EM
    
  • 6x6a, 7crw – hDPP-IX + NLRP1 – Cryo EM
    
  • 6x6c – hDPP-IX + NLRP1 + VbP – Cryo EM
    
• DPP-X
  • 4wjl – hDPP-X extracellular domain
    
• DPP-XI or peptidase S46 or Asp/Glu-specific DPP
  • 4xzy, 4y01, 4y02, 4y04, 6jtb – PgDPP-XI
    
  • 5sdc, 5sdd, 5sde, 5sdf, 5sdg, 5sdi, 5sdj, 5sdk, 5sdl, 5sdm, 5sdn, 5sdo, 5sdp, 5sdq, 5sds, 6jtc – PgDPP-XI + inhibitor
    
  • 7r51 – PgDPP-XI + dipeptide
  • ]]5jwf]], 5jxk, 5jxp – PeDPP-XI – Porphyromonas endodontalis
    
  • 5jxf, 5jwi, 5jwg, 5jy0 – PeDPP-XI + polypeptide
    
• X-Pro DPP
  • 6nff – X-PDPP – Lactobacillus helveticus
    

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel