Factor XIa 3D structures

3D structures of Factor XIa

Updated on 11-March-2023

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• Factor XIa
  • 2j8j, 2j8l – hFXIa A4 domain (residues 290-379) – human – NMR
    
  • 6i58 - hFXIa zymogen (residues 1-625)
• Factor XIa light chain catalytic domain (residues 388-625) inhibitor complex
  • 3bg8 – hFXIa + clavatadine
    
  • 1zpb, 2fda - hFXIa (mutant) + ketothiazole inhibitor
    
  • 4na7, 4na8, 4y8x, 5q0d, 5q0e, 5q0g, 5q0h, 5qck, 5qqp, 5qtt, 5qtu, 5qtv, 5qtw, 5qtx, 5qty - hFXIa + inhibitor
    
  • 4y8z, 5qcl, 5qcm, 5qcn, 6vlu - hFXIa + quinoline inhibitor
    
  • 5e2o, 5exm, 5tks, 5tkt, 5wb6, 6ts4, 6ts5, 6ts6, 6usy, 7v0z, 7v10, 7v11, 7v12, 7v13, 7v14, 7v15, 7v16, 7v17, 7v18 - hFXIa (mutant) + inhibitor
    
  • 4cr5, 4cr9, 4cra, 4crb, 4cre, 4crf, 1ztl, 4ty7, 4wxi, 4d76, 4d7f, 4d7g, 5e2p, 6ts7, 6vlv - hFXIa (mutant) + quinolin inhibitor
    
  • 4y8y - hFXIa + tetrazol inhibitor
    
  • 4crc, 4crd, 3sor, 1zpc, 3sos, 4x6o, 5exn, 5tku, 6c0s - hFXIa (mutant) + tetrazol inhibitor
    
  • 6w50 - hFXIa + pyrimidine inhibitor
    
  • 1ztk, 1ztj, 1zsl, 4crg, 7mbo - hFXIa (mutant) + pyrimidine inhibitor
    
  • 4x6m, 4x6p, 5exl - hFXIa (mutant) + indazole inhibitor
    
  • 4x6n - hFXIa (mutant) + indazole inhibitor + peptide
    
  • 1zhm, 1zhp, 1zhr - hFXIa (mutant) + benzamidine inhibitor
    
  • 1zrk, 1zsk, 1zsj - hFXIa (mutant) + naphthamidine inhibitor
    
  • 1zpz, 1zom - hFXIa (mutant) + peptidomimetic inhibitor
    
  • 1zmn, 1zml, 1zmj, 1zlr - hFXIa (mutant) + aryl boronic acid inhibitor
    
  • 1zjd - hFXIa (mutant) + Kunitz protease inhibitory domain
    
  • 1xx9 - hFXIa + ecotin (mutant)
    
  • 1xxd, 1xxf - hFXIa (mutant) + ecotin (mutant)
    
  • 4ty6 - hFXIa light chain (mutant) + heavy chain peptide + benzamine inhibitor
    
  • 6r8x - hFXIa light chain + antibody
    
  • 6aod, 6hhc - hFXIa light chain (mutant) + antibody
    
  • 6twb, 6twc - hFXIa light chain + peptide
    
  • 5q0f, 5qqo - hFXIa light chain + peptide + inhibitor
    
  • 7qot - hFXIa heavy chain + kiniogen
    

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Michal Harel, Joel L. Sussman