Ketol-acid reductoisomerase 3D structures

3D Structures of Ketol-acid reductoisomerase

Updated on 19-October-2025

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• KARI class I
  • 1np3 – KARI – Pseudomonas aeruginosa
    
  • 4xeh – IaKARI – Ignisphaera aggregans
    
  • 4xiy – KARI + Fe + Mg – Azotobacter vinelandii
    
  • 4ypo – KARI + Mg – Mycobcterium tuberculosis
    
  • 4kqw – SeKARI + NADPH + Mg – Slackia exigua
    
  • 4tsk – KARI + NADPH + Mg – Alicyclobacillus acidocaldarius
    
  • 5yeq – KARI + Mg – Sulfolobus acidocaldarius
    
  • 4xdy – KARI + NADPH + Mg – archea
    
  • 4xdz – IaKARI + NADPH + Mg
    
  • 5w3k, 6aqj – SaKARI + NADPH + Mg – Staphyloccocus aureus
    
  • 6bul, 6c55, 6c5n – SaKARI + NADPH + Mg + hydroxyoxamate inhibitor
    
  • 7ke2, 9b9p, 9bae – SaKARI + Mg + pyrimidine inhibitor
    
  • 7kh7 – SaKARI + NADPH + Mg + pyrimidine inhibitor
    
  • 6vo2 – SaKARI + NADPH + Mg + inhibitor
    
  • 4kqx – SeKARI + NAD + Mg + hydroxyl-isopropyloxamate
    
  • 6jcv, 6jcw, 6kou, 6kpe, 6kpi, 6kpk, 6kq4, 6kq8 – SsKARI + Mg – Saccharolobus solfataricus – Cryo EM
    
  • 6jd2 – SsKARI + Mg
    
  • 6kpa, 6kph, 6kpj, 6kqj, 6kqk, 6kqo – SsKARI + Mg + NAD – Cryo EM
    
  • 6jcz, 6jd1 – SsKARI + NADP + Mg + dicarboxylate derivative – Cryo EM
    
  • 6jx2 – KARI + NADPH + Mg – Corynebacterium glutamicum
    
  • 6l2k, 6l2r, 6l2s, 6l2z – SpKARI (mutant) – Streptococcus pneumoniae
    
  • 6l2i – SpKARI + NADPH + Mg
    
  • 7pci, 7pcm, 7pcn – BtKARI + NADH + Mg + enoate derivative – Burkholderia thailandensis
    
  • 7pcc – BtKARI + NADH + Mg
    
  • 7pco, 7pct – BtKARI (mutant) + NADH + Mg + enoate derivative
    
  • 7pcg – BtKARI + NADH + Mg + bicarboxylate derivative
    
  • 7pcl – BtKARI + NADH + Mg + ethanoate derivative
    
  • 7pce – BtKARI + ADP
    
  • 8ep7 – KARI + NADP + Mg – Bacillus anthracis
    
  • 8cy8 – CjKARI – Campylobacter jejuni – Cryo EM
    
  • 7lat – CjKARI + Mg
    
  • 7rdu, 8upn, 8upp – CjKARI + NADP + Mg
    
  • 8sxd – CjKARI + NADP + nicotinamide + Mg
    
  • 8swm – CjKARI + acetolactate + Mg
    
  • 8upq – CjKARI + isovalerate + Mg
    
  • 7q03 – MtKARI + NADP – Methanothermococcus thermolithotropicus
    
  • 7q07 – MtKARI + NADP + tartarate
    
  • 7toc – KARI + NADP + Mg – Candida auris
    
  • 8pve – TtKARI – Thermus thermophilus
    
  • 8pru – TtKARI + Mg
    
  • 8k32 – KARI + NADH + Mg – Syntrophothermus lipocalidus
    
• KARI class II
  • 3fr7 – rKARI + Mg - rice
    
  • 3fr8 – rKARI + NADPH + Mg
    
  • 9bag – rKARI + inhibitor + Mg
    
  • 1yve – sKARI + NADPH + hydroxyl-isopropyloxamate - spinach
    
  • 1qmg – sKARI + Mn + dihydroxy-valerianate + AMP-diphosphoribose
    
  • 5e4r – KARI + NADPH + Mg – Ignisphaera aggregans
    
  • 1yrl – EcKARI – Escherichia coli
    
  • 3ulk – EcKARI + NADPH + Mg
    

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel