3D structures of LRRK2
Updated on 28-October-2025
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- LRRK2
- 6xr4 – hLRRK2 – human - Cryo EM
- 7li4 – hLRRK2 + ATP + GDP
- 7lht, 7lhw – hLRRK2 + ATP + GDP – Cryo EM
- 7li3 – hLRRK2 (mutant) + ATP + GDP
- 9ci3 – hLRRK2 (mutant) + 14-3-3 protein gamma + GDP – Cryo EM
- 8tzh – hLRRK2 (mutant) + darpin + GDP – Cryo EM
- 8vh4, 8vh5 – hLRRK2 + Rab12 + GDP + GNP – Cryo EM
- 8fo2, 8fo8, 8fo9 – hLRRK2 + Rab29 + GDP + ATP – Cryo EM
- 8u8a, 8u8b – hLRRK2 + GDP + drug – Cryo EM
- 8u7l – hLRRK2 + GDP + inhibitor – Cryo EM
- 9cho – hLRRK2 543-2527 + GDP + inhibitor – Cryo EM
- 8tzf – hLRRK2 + ankyrin repeat protein + GDP + inhibitor – Cryo EM
- LRRK2 GTPase domain 1329-1520
- LRRK2 Roc domain
- 9c76 – hLRRK2 + GDP + drug
- LRRK2 WD40 domain 2142-2527
- 6dlo, 6dlp – hLRRK2 WD40 domain
- 9c61 – hLRRK2 WD40 domain + inhibitor
- LRRK2 C-terminal domain 1330-2527
- 6vp7, 6vp8 – hLRRK2 C-terminal – Cryo EM
- 6vno, 6vp6 – hLRRK2 C-terminal + GDP – Cryo EM
- 8tzb, 8tzc, 8tze, 8tzg – hLRRK2 C-terminal + inhibitor – Cryo EM
- 8fo7, 8smc, 8txz, 8u7h – hLRRK2 C-terminal + GDP + inhibitor – Cryo EM
- 8u1b – hLRRK2 C-terminal + darpin
- 9dmi – hLRRK2 C-terminal + darpin + inhibitor – Cryo EM
- 8tyq – hLRRK2 C-terminal (mutant) + ankyrin repeat protein + inhibitor – Cryo EM
