Mannosidase 3D structures

3D structures of mannosidase

Updated on 29-March-2026

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• α-MAN
  • 1o7d - αMAN – bovine
    
  • 6b9o - jbαMAN – jack bean
    
  • 6lz1 - αMAN – fission yeast – Cryo EM
    
  • 2wvx, 2wvy, 2ww2, 4acy, 4acz, 4ad0, 4c1s - αMAN - Bacterioides thetaiotaomicron
    
  • 1hcu - TrαMAN – Trichoderma reesei
    
  • 7ufr, 7uft - BlaMAN – Bifidobacterium longum – Cryo EM
    
• α-MAN class I
  • 1fmi - hαMAN I - human
    
  • 1fo2 - hαMAN I + deoxymannojirimycin
    
  • 1fo3 - hαMAN I+ kifunensine
    
  • 1x9d - hαMAN I residues 243-699 + polysaccharide analog
    
  • 1nxc - mαMAN I + mannose – mouse
    
  • 6b9p - jbMAN + inhibitor
    
  • 5jm0 - yαMAN I – yeast
    
  • 1dl2 - yαMAN I catalytic domain + mannose
    
  • 1g6i - yαMAN I + deoxymannojirimycin
    
  • 2ri8 - PcαMAN I + glycerol – Penicillium citrinum
    
  • 1kre, 1kkt - PcαMAN I + mannose
    
  • 2ri9 - PcαMAN I + substrate analog
    
  • 1krf - PcαMAN I + kifunensine + mannose
    
• α-MAN class II
  • 3bub, 1hty, 6rpc - DmαMAN II catalytic domain – Drosophila melanogaster
    
  • 3bud - DmαMAN II catalytic domain (mutant)
    
  • 3bui - DmαMAN II catalytic domain (mutant) + Tris
    
  • 3bup, 3buq, 3czs - DmαMAN II catalytic domain (mutant) + mannose
    
  • 6rqz, 6rrh – DmαMAN II + mannose derivative
    
  • 6rrj, 6rrn, 6rru, 6rrw, 6rrx, 6rry, 6rs0, 9ftq, 9ftr – DmαMAN II + aziridine derivative
    
  • 3bvt, 3bvu, 3bvv, 3bvw, 3bvx - DmαMAN II catalytic domain (mutant) + mannopyranoside
    
  • 1r33, 1r34 - DmαMAN II catalytic domain + mannopyranoside
    
  • 3ddf, 3ddg, 2f18, 2f1a, 2f1b - DmαMAN II catalytic domain + pyrrolidin
    
  • 2alw - DmαMAN II catalytic domain + noeuromycin
    
  • 3cv5 - DmαMAN II catalytic domain + polysaccharide
    
  • 3czn - DmαMAN II catalytic domain (mutant) + polysaccharide
    
  • 2wyi - SpαMAN II + swainsonine
    
  • 3blb, 1hww - DmαMAN II + swainsonine
    
  • 3ejp, 3ejq, 3ejr, 3ejs, 3ejt, 3eju, 2ow6, 2ow7 - DmαMAN II catalytic domain + swainsonine analog
    
  • 3dx0, 3dx2, 2f7o - DmαMAN II catalytic domain + mannostatine
    
  • 3dx1, 3dx3, 3dx4, 2f7p - DmαMAN II catalytic domain + mannostatine analog
    
  • 3d4y, 3d4z - DmαMAN II catalytic domain + imidazole derivative
    
  • 3d50, 3d51, 3d52 - DmαMAN II catalytic domain + inhibitor
    
  • 2fyv, 2f7q, 2f7r - DmαMAN II catalytic domain + amino-salacinol carboxylate analog
    
  • 1tqv, 1tqw, 1tqs, 1tqt, 1tqu - DmαMAN II catalytic domain (mutant) + seleno-salacinol
    
  • 1ps3 - DmαMAN II catalytic domain + kifunensine
    
  • 1qwn - DmαMAN II catalytic domain + intermediate
    
  • 1hxk - DmαMAN II catalytic domain + deoxymannojirimycin
    
  • 1qwu - DmαMAN II catalytic domain (mutant) + guloside
    
  • 1qx1 - DmαMAN II catalytic domain (mutant) + mannosyl
    
  • 2wyh - SpαMAN II – Streptococcus pyrogenes
    
• α-1,2-MAN
  • 4ayo – CaαMAN - Caulobacter
    
  • 4ayp, 4ayq, 5meh – CaαMAN + mannose derivative
    
  • 4ayr – CaαMAN + noeuromycin
    
  • 5ne5 – CaαMAN + kifunensine
    
  • 8b5m – CaαMAN + inhibitor
    
  • 5kkb – mαMAN + mannose derivative
    
  • 5kij – hαMAN + mannose derivative
    
  • 5kk7 – hαMAN (mutant) + disaccharide derivative
    
  • 6dwo – EfαMAN – Enterococcus faecalis
    
  • 7fe2 – EfαMAN (mutant) + mannose derivative
    
  • 7nsn – αMAN + mannose derivative – Neobacillus novalis
    
• α-1,3-MAN
  • 7zgm – αMAN – Phocaeicola massiliensis
    
• β-MAN
  • 6ddt - mMAN
    
  • 6ddu - mMAN + β-mannose
    
  • 4jho - rβMAN – rice
    
  • 4jie - rβMAN + β-mannose
    
  • 2je8 - BtβMAN residues 26-864
    
  • 2wbk - BtβMAN residues 26-864 + mannopyranoside
    
  • 2vqt, 2vr4, 2vjx, 2vl4, 2vmf, 2vo5, 2vot, 2vqu - BtβMAN residues 26-864 + piperidine derivative
    
  • 1oh4, 1of4 - TmβMAN catalytic domain + mannose – Thermotoga maritima
    
  • 1of3 - TmβMAN catalytic domain
    
  • 1uz4 - CmβMAN + inhibitor – Cellvibrio mixtus
    
  • 1uuq - CmβMAN
    
  • 2whk - βMAN – Bacillus subtilis
    
  • 4cvu, 4uoj – βMAN - Trichoderma harzianum
    
  • 5n6u - βMAN + β-mannose – Dictyoglomus thermophilum
    
  • 6byc - XaMAN – Xanthomonas axonopodis
    
  • 6byg, 6byi - XaMAN (mutant)
    
  • 6bye - XaMAN + β-mannose
    
  • 4zxo - BoMAN – Bacterioides ovatus
    
  • 2whj - BaMAN – Bacillus agaradhaerens
    
  • 2whl - BaMAN + β-mannose
    
  • 6t5o - BsMAN – Bacterioides salyersiae
    
  • 6t7g - BsMAN + mannose derivative
    
  • 6t6g - BsMAN + noeuromycin
    
  • 6mp2, 6mpa - BlMAN
    
  • 6moy, 6mp7, 6mpc - BlMAN (mutant)
    
  • 7op7 - BtMAN + aziridine derivative
    
• Mannan endo-1,4-β-MAN
  • 2c0h - βMAN (mutant) – blue mussel
    
  • 1rh9 – βMAN – Solanum lycopersicum
    
  • 1gvy, 1odz, 1gw1, 2whm - PcβMAN (mutant) + mannose derivative – Pseudomonas cellulosa
    
  • 1j9y, 1r7o - PcβMAN
    
  • 2whk, 4yn5, 3jug, 2qha - βMAN – Bacillus subtilis
    
  • 3pz9, 3pzg – TpβMAN – Thermotoga petrophila
    
  • 3pzi – TpβMAN + glucose
    
  • 3pzm, 3pzn – TpβMAN + glycerol
    
  • 3pzo, 3pzq – TpβMAN + maltose
    
  • 3ziz - βMAN – Podspora anserina
    
  • 3wh9 - βMAN – Aspergillus niger
    
  • 1qns, 1qnr, 1qnq, 1qnp, 1qno - TrMAN
    
• Endo-α-MAN
  • 4utf - BxαMAN – Bacterioides xylanisolvens
    
  • 4ad5, 4ad4, 4ad3, 4ad2, 4ad1 – BxαMAN + mannose derivative
    
• Endo-α-1,2-MAN
  • 6zdc, 6zdf, 6zdk, 6zfq – hαMAN catalytic domain
    
  • 6zj5 – hαMAN catalytic domain + glucosamine derivative
    
  • 6zj1 – hαMAN catalytic domain (mutant) + glycan fragment
    
  • 6zfn – hαMAN catalytic domain (mutant) + mannobiose
    
  • 6zfa – hαMAN catalytic domain + mannobiose + Glc derivative
    
  • 6zfl – hαMAN catalytic domain + Glc derivative
    
• Endo-α-1,6-MAN
  • 6ry0 - CtαMAN – Chaetonium thermofilum
    
  • 6ry1 – CtαMAN + mannose
    
  • 6ry2, 6ry5 – CtαMAN + mannobiose
    
  • 6ry6 – CtαMAN + glucosamine
    
  • 6ry7 – CtαMAN + laminaribiose
    
• Exo-β-1,4-MAN
  • 4lyp - RmβMAN – Rhizomucor miehei
    
  • 4lyq, 4lyr - RmβMAN (mutant)
    
  • 4nrr - RmβMAN (mutant) + mannosyl-fructose
    
  • 4nrs - RmβMAN (mutant) + mannobiose
    
  • 6gvb - βMAN – Cutibacterium acnes
    
  • 7bob - MAN – Opitutaceae bacterium
    
  • 7odj – CmβMAN + mannose derivative
    
• Exo-α-1,6-MAN
  • 5m7i - CpαMAN (mutant) + mannobiose – Clostridium perfringenes
    
  • 5m7y - CpαMAN (mutant) + mannotriose
    
  • 6rqk - CpMAN + mannoimidazole
    
• β-MAN/β-glucosidase
  • 4re2, 4re3, 4re4 - rβMAN/βGLU
    

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Openfox