N-acetylneuraminate lyase 3D structures

Updated on 12-January-2026

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• N-acetylneuraminate lyase or sialic acid aldolase
  • 6arh – hNANL – human
    
  • 4ah7, 4aho, 4ahp, 5kze, 5lky – SaNANL – Staphylococcus aureus
    
  • 4ahq – SaNANL (mutant)
    
  • 6h4e – NANL – Proteus mirabillis
    
  • 1nal, 2ygy, 3lbm – EcNANL – Escherichia coli
    
  • 3lcf, 3lcg, 3lch, 3lci, 3lcl, 2wnq, 2wo5 - EcNANL (mutant)
    
  • 1f5z, 1f6p – HiNANL – Haemophilus influenzae
    
  • 5zjm – FnNANL – Fusobacterium nucleatum
    
  • 4imc, 4imd – PmNANL – Pasteurelia multocida
    
  • 4ime – PmNANL (mutant)
    
  • 5c54 – CgNANL – Corynebacterium glutamicum
    
  • 4n4p, 4n4q – NANL – Mycoplasmopsis synoviae
    
  • 5afd – NANL – Aliivibrio salmonicida
    
  • 6rab – RgNANL – Ruminococcus gnavus
    
  • 6rb7 – RgNANL (mutant)
    
  • 8u90, 8u91, 8u93 – KaNANL – Klebsiella aerogenes
    
• N-acetylneuraminate lyase complex
  • 5kzd – SaNANL + sialic acid derivative
    
  • 4ama, 5a8g – SaNANL + pyruvate derivative
    
  • 1fdy, 1fdz, 2wnn, 4uui – EcNANL + pyruvate derivative
    
  • 2wnz, 2wkj, 2xfw – EcNANL (mutant) + pyruvate derivative
    
  • 4bwl – EcNANL (mutant) + pyruvate derivative + neuraminate derivative
    
  • 1f7b, 1hl2, 1f6k – EcNANL (mutant) + pyruvate derivative
    
  • 3lbc – EcNANL + L-arabinose
    
  • 2wpb - EcNANL (mutant) + pyruvate + inhibitor
    
  • 3lcx - EcNANL L-KDO (mutant)
    
  • 3lcw - EcNANL L-KDO (mutant) + hydroxypyruvate
    
  • 5zka – FnNANL + pyruvate derivative
    
  • 4imf, 4img – PmNANL (mutant) + neuraminate derivative – Pasteurelia multocida
    
  • 4woz – CdNANL + mannoseamine – Clostridium dificile
    
  • 4woq – CdNANL + ketobutyric
    
  • 1f73, 1f74 – HiNANL + sialic acid derivative
    
  • 5c55 – CgNANL (mutant) + pyruvate derivative
    
  • 8u8w, 8u92, 8ur1 – KaNANL + pyruvate derivative
    
  • 6rb7, 6rd1 - RgNANL (mutant) + sialic acid
    

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel