Prostaglandin F synthase 3D structures

Updated on 21-July-2026

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• AKR1C3
  • 4f40 – LmAKR1C3 – Leishmania major
    
  • 4fzi – TcAKR1C3 – Trypanosoma cruzi
    
• AKR1C3 binary complex with NADP
  • 1s1p, 1s1r, 2fgb, 7c7f – hAKR1C3 + NADP - human
    
  • 4dz5 – hAKR1C3 (mutant) + NADP
    
  • 1vbj – AKR1C3 + NADP – Trypanosoma brucei
    
  • 4g5d – LmAKR1C3 + NADP
    
  • 4gie – TcAKR1C3 + NADP
    
• AKR1C3 ternary complex with NADP
  • 1s2a, 1s2c, 3r43, 3r58, 3r6i, 3r7m, 3r8g, 3r8h, 3r94, 3ufy, 4hmn, 4h7c, 4wdu, 4wdt, 4wdw, 4wdx, 4wrh, 4xvdf, 4xve, 4yvv, 4yvx, 4zfc – hAKR1C3 + NADP + NSAID drug
    
  • 1xf0, 8rrj – hAKR1C3 + NADP + androstane derivative
    
  • 1ry0 – hAKR1C3 + NADP + PGD2
    
  • 1ry8, 1zq5, 4dbs, 4dbu, 4fa3, 4fal, 4fam, 5hnt, 5hnu, 6f2u, 6f78, 6a7b, 6gxk, 7wqm, 7wqr, 7wqs, 7x3l, 7x3m, 7x3o, 8bbs, 8i0c, 8jf1, 8rb6, 9ffd, 9jrp, 9jru – hAKR1C3 + NADP + inhibitor
    
  • 7c7g, 7c7h, 9jt4, 9jt5, 9jt6, 9uj1 – hAKR1C3 + NADP + chromene derivative
    
  • 2f38 – hAKR1C3 + NADP + glaucoma drug
    
  • 3uwe – hAKR1C3 + NADP + phenoxybenzoic acid
    
• Prostamide/prostaglandin F synthase
  • 9us9 – hPPGFS
    
  • 9usa – hPPGFS (mutant)
    

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Michal Harel