Receptor protein serine/threonine kinases

spinqualitylabelsall models Human hTGFR-II extracellular domain (green) complex with TGF-β3 (grey) (PDB code 1ktz) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D See also Serine/threonine protein kinase. The systematic name of this enzyme class is ATP:receptor-protein phosphotransferase. Proteins from this group participate in 7 metabolic pathways: MAPK signaling pathway, cytokine-cytokine receptor interaction, TGF beta signaling pathway, adherens junction, colorectal cancer, pancreatic cancer, and chronic myeloid leukemia. TGF-beta receptor TGF-beta receptor Activin receptor Activin receptor 3D structure of the kinase domain of Activin receptor1 (Acvr1) complex with inhibitor shows the inhibitor forming various interactions with the protein including a hydrogen bonds to His residues and a water bridged hydrogen bond to the catalytic lysine. Water molecule is shown as red sphere. Receptor-like serine/threonine protein kinase Crystal structure of the extracellular domain of the receptor-like kinase TMK3 from Arabidopsis thaliana Overall structure of TMK3-LRR domain. 1st orientation Overall structure of TMK3-LRR domain. 2nd orientation. The LRRNT, LRRs (numbered as indicated) and the non-LRR region of TMK3-LRR are colored in green, whitesmoke and blue, respectively. The three disulfide bonds (Cys54-Cys61, Cys315-Cys323 and Cys353-Cys361) are depicted in yellow. “N” and “C” represent N- and C-terminus, respectively.

Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky