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You may include any references to papers as in: the use of JSmol in Proteopedia [1] or to the article describing Jmol [2] to the rescue.
Function of your protein
The function of the protein LDMS is to play a large role in Staphylococcal sulfur amino acid metabolism. On the image, you can see the backbone of the structure, (faintly colored), the amino acids, (in the center and brightly colored), and the ligands ADP and other ions floating around the molecule. LdmS commonly exists in an open state with the P-loop and N-loop disordered.
Biological relevance and broader implications
The protein seems to play an important role in the bacteria Staphylococcus aureus. Scientist are trying to understand the process better to manipulate its metabolism and create better antibiotics The protein seems to mostly be active in gram-positive bacteria
Important amino acids
Amino Acids 300-304 are an important part of the drug binding site [3].
Structural highlights
This is a sample scene created with SAT to color by Group, and another to make a transparent representation of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.
- ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:https://dx.doi.org/10.1002/ijch.201300024
- ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
- ↑ 35988643