Updated on 21-November-2023
{"openlevels":0}
- Son of sevenless 1; Domains - HD histone domain 1-191; DH Dbl homology 203-389; PH pleckstrin homology 443-548; REM+catalytic 601-1020
- 3ksy - hSOS1 - human
- 1q9c - hSOS1 HD
- 1awe - hSOS1 PH - NMR
- 2ii0 - hSOS1 REM+catalytic domains
- 1dbh - hSOS1 DH+PH domains
- 1xd4, 1xdv - hSOS1 DH+PH+REM+catalytic domains
- 1pms - mSOS1 PH (mutant) - mouse - NMR
- Son of sevenless 1 complex
- 1bkd - hSOS1 REM+catalytic domains + HRas
- 1xd2 - hSOS1 REM+catalytic domains + HRas + GDP
- Son of sevenless 1 homolog REM+catalytic domains
- 5ovd - hSOS1 (mutant)
- 6scm, 6sfr, 7avi, 7avl, 7avs, 7avt, 7avu, 7avv, 7avs, 7ukr, 7uks - hSOS1 + inhibitor
- 5ove, 5ovg, 5ovf 5ovi, 5ovh - hSOS1 (mutant) + inhibitor
- 8be2 - hSOS1 + nanobody
- 1nvx, 1nvu - hSOS1 + HRas + GTP
- 1nvw, 1nvv - hSOS1 + HRas + GNP
- 4uru, 4urv, 4urw, 4urx, 4ury, 4urz, 4us0, 4us1, 4us2 - hSOS1 + HRas + ligand
- 8be6, 8be7, 8be8, 8be9, 8bea - hSOS1 + HRas + peptidomimetic
- 4nym, 6bvi, 6bvk, 6bvj, 6bvm, 6bvl, 6cuo, 6cup, 6cur, 6d55, 6d56, 6d59, 6d5e, 6d5g, 6d5h, 6d5j, 6d5l, 6d5w, 6d5v, 6d5m, 6v9o - hSOS1 + HRas + GNP + activator
- 4nyi, 4nyj, 5wfo, 5wfq, 5wfp, 5wfr, 6v94, 6v9j, 6v9l, 6v9n, 6v9m, 6v9f - hSOS1 + HRas + GNP + inhibitor
- 6epl - hSOS1 REM+catalytic domains (mutant) + KRas
- 8be4, 8be5 - hSOS1 + KRas + nanobody
- 7kfz - hSOS1 + KRas + GNP – Cryo EM
- 6epn, 6epm, 6epp, 6epo - hSOS1 + KRas + inhibitor
- Son of sevenless 2
- 6eie - hSOS2 REM+catalytic domains (mutant)
