Uploads by Cody Couperus

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File list
Date Name Thumbnail Size Description Versions
12:41, 30 April 2014 Substrates.png (file) 20 KB Overview of thrombin substrates 1
07:57, 30 April 2014 Prothrombin activation scheme 3.png (file) 40 KB   1
07:56, 30 April 2014 Prothrombin activation scheme nofva3.png (file) 38 KB Activation scheme of in vivo activation of prothrombin by FXa in the absence of FVa 1
06:19, 30 April 2014 Cation pi.png (file) 132 KB A cation-π interaction between Trp128 and Arg 129 in alpha thrombin (PDB: 2BDY). The guanidinium carbon is 3.6 angstroms from the top edge of the Trp. It is expected that the epsilon nitrogen forms the primary cation-π interaction. The electrostatic and 1
06:17, 30 April 2014 Capping.png (file) 125 KB “Capping box” motif in alpha thrombin (PDB: 1PPB) represented by His230 (Ncap) side chain and main chain hydrogen bonded with the backbone nitrogen of Arg233 (N3) (Aurora & Rose, 1998; Doig, MacArthur, Stapley, & Thornton, 1997). An additional feature 1
01:42, 30 April 2014 Prothrombinase ternary model.pdb (file) 2.74 MB   3
03:02, 28 April 2014 Electrostatic labeled.png (file) 611 KB Thrombin (1PPB) overlayed with electrostatic surface. Structural features 60-loop, gamma loop, exosite I, and exosite II labeled. 1