Uploads by Cristina Murga

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File list
Date Name Thumbnail Size Description
14:42, 30 November 2023 Organos OAT.png (file) 168 KB (Nigam et al., 2015)
14:39, 30 November 2023 Estructura OAT.jpeg (file) 26 KB (Zhang et al., 2021)
12:00, 30 November 2023 Organos.png (file) 182 KB  
21:33, 29 November 2023 OAT transporter.jpeg (file) 26 KB Figure 1: Structure of OAT transporters.
19:15, 25 November 2023 8SDU.cif (file) 368 KB  
13:55, 25 November 2023 Molecular dynamics simulation of OAT1.png (file) 116 KB Molecular dynamics simulation of the part of OAT1 closer to its extracellular face (A), part closer to its intracellular face (B) and the 4 helices that participate in the tilt (C). (Tsigelny et al., 2011)
14:55, 10 December 2012 PONATINIB.jpg (file) 38 KB Ponatinib bound to Abl
22:09, 9 December 2012 Figura1jc.jpg (file) 27 KB Figure has been adapted from Cell, Vol. 112, 859–871, March 21, 2003, Copyright 2003 by Cell Press “Structural Basis for the Autoinhibition of c-Abl Tyrosine Kinase”
18:24, 9 December 2012 Imatinib bound to receptor.PNG (file) 9 KB  
11:58, 9 December 2012 Nilotinib in binding site.PNG (file) 5 KB  
23:15, 5 December 2012 Foto1prv.jpg (file) 66 KB Figure 2: this figure has been adaptated from Nature Reviews Drug Discovery 3; 1001-1010 (2004); doi:10.1038/nrd1579 and Protein kinases: evolution of dynamic regulatory proteins (Susan S. Taylor and Alexandr P. Kornev)
23:37, 4 December 2012 Almu reaction.jpg (file) 81 KB  
13:42, 9 December 2010 Reaccion cox.png (file) 19 KB