Uploads by James Lignos
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This special page shows all uploaded files.
| Date | Name | Thumbnail | Size | Description |
|---|---|---|---|---|
| 14:37, 30 April 2025 | PfBDP1 BRD BP 2025-04-30 at 10.32.42 AM.png | PfBDP1_BRD_BP_2025-04-30_at_10.32.42 AM.png | 512 KB | |
| 14:24, 30 April 2025 | PfBDP1 BRD in complex with RMM2 3-30-25.png (file) |  |
512 KB | PfBDP1_BRD_with_RMM2_3:30:25.png |
| 16:47, 29 April 2025 | PfbDP1 BRD BP.png (file) |  |
516 KB | PfbDP1_BRD_BP.png |
| 16:46, 29 April 2025 | PfBDP1 BRD BP.png (file) |  |
516 KB | PfBDP1_BRD_BP.png |
| 14:27, 27 April 2025 | BRD Mechanism.jpg (file) |  |
111 KB | Bromodomains are epigenetic "readers" that bind to acetylated lysines on N-terminal histone tails. Histone acetylation is a post translational modification that is associated with regions of chromatin that are primed for transcription. Bromodomains bind t |
| 16:02, 26 April 2025 | PfBDP1 inhibition.png (file) |  |
212 KB | Cartoon depiction of drug based rationale for targeting the bromodomain of PfBDP1 to block its interaction with chromatin ligands at the promoters of genes implicated in host cell invasion as a strategy to combat malaria. |
| 15:59, 26 April 2025 | PfBDP1 inhibition.pdf (file) |  |
186 KB | Cartoon depiction of drug based rationale for targeting the bromodomain of PfBDP1 to block its interaction with chromatin ligands at the promoters of genes implicated in host cell invasion as a strategy to combat malaria. |
| 15:54, 26 April 2025 | PfBDP1 Inhibition Schematic.png (file) |  |
212 KB | Cartoon depiction of drug based rationale for targeting the bromodomain of PfBDP1 to block its interaction with acetylated chromatin ligands at the promoters of genes implicated in host cell invasion as a strategy to combat malaria. |
| 15:54, 26 April 2025 | PfBDP1 Inhibition schematic.png (file) |  |
212 KB | Cartoon depiction of drug based rationale for targeting the bromodomain of PfBDP1 to block its interaction with acetylated chromatin ligands at the promoters of genes implicated in host cell invasion as a strategy to combat malaria. |
| 15:53, 26 April 2025 | Screenshot 2025-04-26 at 11.44.58 AM.png | Screenshot_2025-04-26_at_11.44.58 AM.png | 212 KB | Cartoon depiction of drug based rationale for targeting the bromodomain of PfBDP1 to block its interaction with acetylated chromatin ligands at the promoters of genes implicated in host cell invasion as a strategy to combat malaria. |
| 15:50, 26 April 2025 | Screenshot 2025-04-26 at 11.44.58 AM.pdf | Screenshot_2025-04-26_at_11.44.58 AM.pdf | 186 KB | Cartoon depiction of drug based rationale for targeting the PfBDP1 bromdodomain to block the interaction between chromatin ligands and PfBDP1 at the promoters of genes implicated in host cell invasion as a strategy to combat malaria. |
