Uploads by Jan Hamalcik
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This special page shows all uploaded files.
| Date | Name | Thumbnail | Size | Description |
|---|---|---|---|---|
| 22:08, 22 May 2019 | Stereo picture of the CBS' heme binding pocket.png (file) |  |
332 KB | Stereo picture of the heme binding pocket. Atoms are colour-coded according to atom type (grey: carbon, red: oxygen, blue: nitrogen, green: phosphorus); mutated residues are labelled and their carbon atoms are coloured in magenta. == Licensing == PMID: 1 |
| 22:03, 22 May 2019 | Stereo picture of the CBS' active site.png (file) |  |
288 KB | Stereo picture of the active site. Atoms are colour-coded according to atom type (grey: carbon, red: oxygen, blue: nitrogen, green: phosphorus); mutated residues are labelled and their carbon atoms are coloured in magenta. Hydrogen bonds between the PLP c |
| 20:16, 28 April 2019 | CBS NewCartoon.gif (file) |  |
1.04 MB | Molecular dynamical simulation of the CBS enzyme computed with CHARMM in MetaCentrum MO. Visualization in VMD, graphically represented with NewCartoon. |
| 20:13, 28 April 2019 | CBS Lines.gif (file) |  |
1.23 MB | Molecular dynamical simulation of the solvated and ionized CBS enzyme computed with CHARMM in MetaCentrum MO. Visualization in VMD, graphically represented with lines. |
| 19:48, 28 April 2019 | Homocysteine metabolic pathway.png (file) |  |
296 KB | Homocysteine metabolic pathway. Homocysteine sits at the intersection of the remethylation and transsulfuration pathways. In the remethylation pathway, THF is converted to N5,N10-methylene tetrahydrofolate and then to MTHF by methylenetetrahydrofolate red |
| 19:46, 28 April 2019 | Proposed enzymatic mechanism for the CBS.png (file) |  |
122 KB | Proposed enzymatic mechanism for the CBS reaction with absorption maxima. Possible quinonoid intermediates between E-serine (E-PLP-L-ser) and E-aminoacrylate (E-PLPaa) or between E-aminoacrylate and E-cystathionine are not shown. The growing consensus amo |
| 19:35, 28 April 2019 | Reactions catalyzed by CBS.png (file) |  |
56 KB | Reactions catalyzed by CBS. (A) Canonical reaction of CBS. (B) CBS reactions that generate or utilize H2S. |
