TRNA-guanine transglycosylase 3D structures

3D structures of tRNA-guanine transglycosylase

Updated on 23-January-2024

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• tRNA-guanine transglycosylase
  • 6h42 – hTGT catalytic subunit – human
    
  • 6fv5 – mTGT non-catalytic subunit – mouse
    
  • 7ov9 – mTGT catalytic + accessory subunits
    
  • 7b2i – mTGT catalytic + accessory subunits (mutant)
    
  • 6h62 – mTGT catalytic subunit
    
  • 1pud, 1p0d, 4pun – ZmTGT – Zymomonas mobilis
    
  • 1wkd, 1wke, 1wkf, 1ozm, 2oko, 2z1v, 2nso, 3bl3, 3hfy, 4gd0, 4h6e, 3unt, 3uvi, 4dxx, 4dy1, 4htb, 4ipp, 4jbr, 4l56, 4q8m, 4q8n, 6h7c, 6ygm, 6yry, 6yfx, 6yfw, 6z0d, 7a0b, 7a3v, 7a3x, 7a4k, 7a4x, 7a6d, 7a9e, 7adn, 7apm, 7apl – ZmTGT (mutant)
    
  • 2ash – TGT – Thermotoga maritima
    
• tRNA-guanine transglycosylase complexes
  • 6h45 – hTGT + queuine
    
  • 7nq4 – hTGT catalytic + accessory subunits + RNA
    
  • 8omr – hTGT catalytic + accessory subunits + tRNA-Asp
    
  • 7ovs – mTGT catalytic (mutant) + accessory subunits (mutant) + W
    
  • 7ovo – mTGT catalytic (mutant) + accessory subunits (mutant) + queuine
    
  • 7owz – mTGT catalytic (mutant) + accessory subunits (mutant) + W + queuine
    
  • 1p0e – ZmTGT + preQ1
    
  • 1efz, 1pxg, 1ozq, 2z1x, 2nqz, 3bld, 4gcx, 4e2v – ZmTGT (mutant) + preQ1
    
  • 3bll – ZmTGT (mutant) + preQ1 derivative
    
  • 1p0b, 2qii – ZmTGT + preQ0
    
  • 2pwv – ZmTGT (mutant) + preQ0
    
  • 3blo, 4hqv, 4hsh, 4hvx – ZmTGT (mutant) + queuine
    
  • 1enu, 1f3e – ZmTGT + aminophthalhydrazide
    
  • 1r5y, 1q4w, 1q63, 1q65, 1q66, 1s38, 1s39, 1y5v, 1y5w, 1y5x, 2bbf, 2qzr, 3eos, 3eou, 3gc4, 1k4g, 1k4h, 3gc5, 3ge7, 4puj, 4puk, 4q4o, 4q4p, 4q4q, 4q4r, 4q4s, 4q8t, 4q4u, 4q8v, 4q8w, 5jxq, 5jsw, 5jxq, 5lpo, 5lpp, 5lpq, 5lps, 5lpt, 3c2y, 5i00, 5i02, 5i03, 5i06, 5i07, 5jgm, 5jgo, 5jsv, 6rkq, 6rkt – ZmTGT + quinazoline inhibitor
    
  • 4pul, 4pum, 4q8o, 4q8p, 4q8q, 6fmn, 6fpu, 6yh3, 6h7c, 6ygk, 6ygl, 6ygo 6ygp, 6ygs, 6ygy, 6ygx, 6ygw, 6ygz, 6yh1, 6ygr, 6yhe, 6yiq, 6yyz, 6yhd – ZmTGT (mutant) + quinazoline inhibitor
    
  • 4q4m – ZmTGT + triazine inhibitor
    
  • 5egr, 5sw3, 5v3c, 5utj – ZmTGT + inhibitor
    
  • 6yh2 – ZmTGT (mutant) + inhibitor
    
  • 1n2v, 2z1w – ZmTGT + pyridazine derivative
    
  • 5sw3, 6fso – ZmTGT + pyridine derivative
    
  • 5utj – ZmTGT + azapurine derivative
    
  • 5v3c – ZmTGT + cyclohexane derivative
    
  • 1q2r, 1q2s – ZmTGT + RNA
    
  • 5n6f – ZmTGT + guanine
    
  • 2pot, 2pwu, 4h7z – ZmTGT (mutant) + guanine
    
  • 5uti – ZmTGT + canavanine
    
  • 2z7k, 3rr4, 3tll, 4fr6, 4fsa, 4fr1, 4fps, 4gi4, 4giy, 4gkt, 4kwo, 4lbu, 4leq, 5i09 – ZmTGT + benzoguanine derivative
    
  • 5j9m, 5j9n, 5j9o, 5jt5, 5jt6, 5jt7 – ZmTGT + benzoimidazole derivative
    
  • 3s1g, 3sm0, 4gg9, 4gh1, 4gh3, 4ghr – ZmTGT + benzohypoxanthine derivative
    
• Archaebacterial tRNA-guanine transglycosylase
  • 1iq8 – PhATGT – Pyrococcus horikoshii
    
  • 1it7 – PhATGT + guanine
    
  • 1it8 – PhATGT + preQ0
    
  • 1j2b – PhATGT + tRNA-Val
    

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Michal Harel