Telomerase 3D structures

Telomerase 3D structures

Updated on 29-March-2026

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• Telomerase reverse transcriptase
  • 5c9h – hTERT + RNA - human
    
  • 4mnq – hTERT + MHC + b-2-microglobulin + T cell receptor
    
  • 5ugw – hTERT thumb domain
    
  • 7bg9, 7bgb – hTERT H/ACA RNP lobe – Cryo EM
    
  • 7qxa – hTERT + TPP1 + DNA – Cryo EM
    
  • 7qxb, 7qxs, 7trd, 7tre, 7trf – hTERT + TPP1 + POT1 + DNA – Cryo EM
    
  • 4lmo – TERT RNA binding domain - puffer
    
  • 4o26 – TERT + telomerase TR – rice fish
    
  • 3du6, 3du5 - rfbTERT catalytic subunit - red flour beetle
    
  • 5cqg - rfbTERT + inhibitor
    
  • 3kyl, 6e53, 6uso, 6usq, 6usp - rfbTERT + DNA
    
  • 7kqm, 7kqn - rfbTERT telomerase catalytic subunit + DNA + RNA
    
  • 6usr - rfbTERT + DNA + G2P
    
  • 2r4g - TtTERT telomerase catalytic subunit 1-1117 - Tetrahymena thermophila
    
  • 2b2a - TtTERT telomerase catalytic subunit (mutant)
    
  • 7lma, 7lmb – TtTERT + telomerase-associated protein + RNA + DNA – Cryo EM
    
  • 7uy6, 7uy7, 8gap – TtTERT catalytic subunit + P50 + P65 + TEB1 + TEB2 + TEB3 + RNA + DNA – Cryo EM
    
  • 7uy5 – TtTERT catalytic subunit + P50 + P65 + TEB1 + TEB2 + TEB3 + telomerase-associated protein + RNA + DNA – Cryo EM
    
  • 6d6v – TtTERT + telomerase-associated protein + TEB2 + RNA + DNA – Cryo EM
    
  • 5c9h - TtTERT catalytic subunit + DNA
    
  • 5lgf - OgTERT N-terminal - Ogataea polymorpha - NMR
    
  • 5npt – OgTERT N-terminal
    
  • 6zd1, 6zd2, 6zd6 - CaTERT – Candida albicans
    
  • 6zdp, 6zdq, 6zdu - CaTERT + RNA
    
  • 7sbe – KlTERT RNA-binding domain 171-404 - Kluyveromyces lactis
    
• Telomerase RNA
  • 7trc, 7v99, 7v9a - hTERC in telomerase holoenzyme – Cryo EM
    
  • 1q75, 2k96 – hTERC P2b hairpin (mutant) – human – NMR
    
  • 2k95, 1na2 - hTERC P2b hairpin – NMR
    
  • 2l3e - hTERC P2a P2b hairpin – NMR
    
  • 2qh2 - hTERC CR7– NMR
    
  • 1ymo - hTERC stem loop IV – NMR
    
  • 1z31 - hTERC Pj6 hairpin – NMR
    
  • 2kye - hTERC P6.1 hairpin – NMR
    
  • 2qh3, 2qh4 - hTERC terminal hairpin loop – NMR
    
  • 5kqe - TERC P2b hairpin – Oryzias latipes - NMR
    
  • 2fey - TtTERC P2b hairpin – NMR
    
  • 5kmz - TtTERC pseudoknot – NMR
    
  • 2m21 - TtTERC stem loop IV – NMR
    
  • 2m22 - TtTERC helix II – NMR
    
  • 2mhi - TERC CR4/5 – medaka - NMR
    
  • 2m8k - KlTERC pseudoknot - NMR
    
  • 8bh9, 8bh8 - TERC + EST1 – Candida tropicalis
    

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Openfox, Jaime Prilusky