Template:STRUCTURE 1d5r

Ligands:

TLA

Activity:

Protein-tyrosine-phosphatase, with EC number 3.1.3.48

Structural annotation:
Resources:	CATH : 1D5Ra02, 1D5Ra01 InterPro : Ipr014020, Ipr000340, Ipr000387, Ipr008973, Ipr000242, Ipr014019 Pfam : PF00782 SCOP : d1d5ra1, d1d5ra2 UniProt : P60484

Functional annotation:
Cellular component:	cytoplasm
Biological process:	phosphoinositide dephosphorylation induction of apoptosis cardiac muscle development cell migration heart development angiogenesis negative regulation of cell cycle regulation of protein stability dephosphorylation inositol phosphate dephosphorylation negative regulation of apoptosis cell cycle negative regulation of protein kinase B signaling cascade central nervous system development lipid metabolic process negative regulation of focal adhesion formation endothelial cell migration regulation of cyclin-dependent protein kinase activity cell proliferation negative regulation of cell migration protein amino acid dephosphorylation negative regulation of cell proliferation
Molecular function:	protein binding phosphoric monoester hydrolase activity lipid binding inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity PDZ domain binding protein tyrosine/serine/threonine phosphatase activity phosphoprotein phosphatase activity phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity hydrolase activity phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity protein tyrosine phosphatase activity protein serine/threonine phosphatase activity phosphatidylinositol-3-phosphatase activity

Evolutionary conservation:

Toggle Conservation Colors:	Rows = identical sequences:
Further Information:	Caveats, Explanation, Complete Results at ConSurfDB

Resources:

FirstGlance, OCA, RCSB, PDBsum

Coordinates:

save as pdb, mmCIF, xml

Proteopedia Page Contributors and Editors (what is this?)