Uridine phosphorylase

spinqualitylabelsall models Structure of uridine phosphorylase complex with fluorouracil, glycerol, ethylene glycol and K+ ion (purple) (PDB code 4e1v). Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Function Uridine phosphorylase (UPP) catalyzes the conversion of uridine or deoxyuridine and phosphate to uracil and α-D-ribose 1-phosphate. UPP is part of RNA or DNA biosynthesis. Unhydrouridine is an inhibitor of UPP. Relevance UPP inhibitors are tested for prevention of mucositis during chemotherapy. Structural highlights The active site of UPP contains the uracil product. Water molecule is shown as red sphere. 3D Structures of uridine phosphorylase Uridine phosphorylase 3D structures

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