User:Karsten Theis/FadA5 thiolase

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Structure of Fad A5

spinqualitylabelsall models Fad A5 thiolase Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D FadA5 thiolase has three subdomains (I: 1-125,246-266; II: 126-245; III: 267-391) and forms a dimer. The following structures have been determined: 4ubv Acetylated FadA5 in complex with CoA 4ubw FadA5 on its own 4ubu The inactive C93S variant in complex with CoA 4ubt The inactive C93S variant in complex with a cleaved product (CoA and a cholesterol acetylated CoA binds to FadA5 Same with labels connect 2.5 4.0 (visible and WAT)(visible) HBOND blue: 177, 221, 224, 242, 243, 151 green: 377, 315, 317, 343, 173, orange: 17, 248, 246, 93 all: 377, 315, 317, 343, 173, 177, 221, 224, 242, 243, 151, 17, 248, 246, 93

References

https://dx.doi.org/10.1016/j.str.2014.10.010

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Karsten Theis