Cytochrome C Oxidase is a membrane bound enzyme here
This enzyme has two heme groups. The heme group receives the electrons from the first copper center
This enzyme has three copper centers placed in two different areas of the electron transfer sequence.
This enzyme pumps proton through the D channel. The entrance to this channel is the Asp-132/Asn-139 gate. Some waters are found in the D-channel
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Function
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Disease
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Structural highlights
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- ↑ Role of aspartate 132 at the orifice of a proton pathway in cytochrome c oxidase. Ann-Louise Johansson, Martin Högbom, Jens Carlsson, Robert B. Gennis, and Peter Brzezinski
DOI: 10.1073/pnas.1303954110