View source for 21ft


==GABA aminotransferase from Arabidopsis thaliana==
<StructureSection load='21ft' size='340' side='right'caption='[[21ft]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[21ft]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=21FT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=21FT FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=21ft FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=21ft OCA], [https://pdbe.org/21ft PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=21ft RCSB], [https://www.ebi.ac.uk/pdbsum/21ft PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=21ft ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GATP_ARATH GATP_ARATH] Transaminase that degrades gamma-amino butyric acid (GABA) and uses pyruvate or glyoxylate as amino-group acceptor, but not 2-oxoglutarate. The pyruvate-dependent activity is reversible while the glyoxylate-dependent activity is irreversible. Cannot use beta-alanine, ornithine, acetylornithine, serine, glycine, asparagine, glutamine, glutamate, valine, leucine, isoleucine, methionine, phenylalanine, histidine, lysine, arginine, aspartate, threonine, tyrosine, tryptophan, proline, or cysteine as amino donors. Modulates steady-state GABA levels in diploid pistil cells and the haploid pollen tube. Involved in the formation of a gradient of GABA along the pollen tube path. Involved in the maintenance of the shoot apical meristem (SAM) structure and subsequent adaxial-abaxial axis-dependent development of cotyledons and leaves (PubMed:21690177).<ref>PMID:12859897</ref> <ref>PMID:17971036</ref> <ref>PMID:19264755</ref> <ref>PMID:21690177</ref> [UniProtKB:P12995]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Arabidopsis thaliana]]
[[Category: Large Structures]]
[[Category: Kobata K]]
[[Category: Nagata K]]
[[Category: Okoda N]]
[[Category: Okuda S]]
[[Category: Sano K]]
[[Category: Tsutsumi K]]