View source for 2quq


==Crystal Structure of the Essential Inner Kinetochore Protein Cep3p==
<StructureSection load='2quq' size='340' side='right'caption='[[2quq]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2quq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QUQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QUQ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2quq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2quq OCA], [https://pdbe.org/2quq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2quq RCSB], [https://www.ebi.ac.uk/pdbsum/2quq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2quq ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CBF3B_YEAST CBF3B_YEAST] Acts as a component of the centromere DNA-binding protein complex CBF3, which is essential for chromosome segregation and movement of centromeres along microtubules. CBF3 is required for the recruitment of other kinetochore complexes to CEN DNA. It plays a role in the attachment of chromosomes to the spindle and binds selectively to a highly conserved DNA sequence called CDEIII, found in centromers and in several promoters.

==See Also==
*[[Centromere protein 3D structure|Centromere protein 3D structure]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Bellizzi III JJ]]
[[Category: Harrison SC]]