2quq
From Proteopedia
Jump to navigationJump to search
Crystal Structure of the Essential Inner Kinetochore Protein Cep3p
| ||||||||||||
Structural highlights
FunctionCBF3B_YEAST Acts as a component of the centromere DNA-binding protein complex CBF3, which is essential for chromosome segregation and movement of centromeres along microtubules. CBF3 is required for the recruitment of other kinetochore complexes to CEN DNA. It plays a role in the attachment of chromosomes to the spindle and binds selectively to a highly conserved DNA sequence called CDEIII, found in centromers and in several promoters. See AlsoContents | ||||||||||||||||||
This page was last modified 09:18, 21 February 2024.