View source for 3j68


==Structural mechanism of the dynein powerstroke (pre-powerstroke state)==
<SX load='3j68' size='340' side='right' viewer='molstar' caption='[[3j68]], [[Resolution|resolution]] 30.00&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3j68]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Strongylocentrotus_purpuratus Strongylocentrotus purpuratus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J68 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3J68 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 30&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3j68 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j68 OCA], [https://pdbe.org/3j68 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3j68 RCSB], [https://www.ebi.ac.uk/pdbsum/3j68 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3j68 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DYHC_YEAST DYHC_YEAST] Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Required to maintain uniform nuclear distribution in hyphae. May play an important role in the proper orientation of the mitotic spindle into the budding daughter cell yeast. Probably required for normal progression of the cell cycle.<ref>PMID:15642746</ref> 

==See Also==
*[[Dynein 3D structures|Dynein 3D structures]]
== References ==
<references/>
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[[Category: Large Structures]]
[[Category: Strongylocentrotus purpuratus]]
[[Category: Lin J]]
[[Category: Nicastro D]]
[[Category: Okada K]]
[[Category: Raytchev M]]
[[Category: Smith MC]]