View source for 4dyu


==The crystal structure of DNA starvation/stationary phase protection protein Dps from Yersinia pestis KIM 10==
<StructureSection load='4dyu' size='340' side='right'caption='[[4dyu]], [[Resolution|resolution]] 2.75&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4dyu]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Yersinia_pestis_KIM10+ Yersinia pestis KIM10+]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DYU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DYU FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.75&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4dyu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dyu OCA], [https://pdbe.org/4dyu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4dyu RCSB], [https://www.ebi.ac.uk/pdbsum/4dyu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4dyu ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DPS_YERPE DPS_YERPE] During stationary phase, binds the chromosome non-specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction.[HAMAP-Rule:MF_01441]

==See Also==
*[[Ferritin 3D structures|Ferritin 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Yersinia pestis KIM10+]]
[[Category: Anderson WF]]
[[Category: Gu M]]
[[Category: Joachimiak A]]
[[Category: Kwon K]]
[[Category: Tan K]]