View source for 4ldr


==Structure of the S283Y mutant of MRDI==
<StructureSection load='4ldr' size='340' side='right'caption='[[4ldr]], [[Resolution|resolution]] 2.29&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4ldr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LDR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LDR FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.292&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ldr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ldr OCA], [https://pdbe.org/4ldr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ldr RCSB], [https://www.ebi.ac.uk/pdbsum/4ldr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ldr ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MTNA_HUMAN MTNA_HUMAN] Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Independently from catalytic activity, promotes cell invasion in response to constitutive RhoA activation by promoting FAK tyrosine phosphorylation and stress fiber turnover.<ref>PMID:19620624</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Metzner SI]]
[[Category: Sousa MC]]
[[Category: Templeton PD]]