View source for 4rco


==1.9 Angstrom Crystal Structure of Superantigen-like Protein, Exotoxin from Staphylococcus aureus, in Complex with Sialyl-LewisX.==
<StructureSection load='4rco' size='340' side='right'caption='[[4rco]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4rco]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_NCTC_8325 Staphylococcus aureus subsp. aureus NCTC 8325]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RCO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4RCO FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene>, <scene name='pdbligand=PRD_900122:Sialyl-Lewis+X+antigen,+alpha+anomer'>PRD_900122</scene>, <scene name='pdbligand=SIA:O-SIALIC+ACID'>SIA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4rco FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rco OCA], [https://pdbe.org/4rco PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4rco RCSB], [https://www.ebi.ac.uk/pdbsum/4rco PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4rco ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SSL4_STAA8 SSL4_STAA8] Secreted protein that plays a role in immune innate response inhibition by interfering with host TLR2-mediated pathway.<ref>PMID:22714643</ref> <ref>PMID:28858870</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Staphylococcus aureus subsp. aureus NCTC 8325]]
[[Category: Anderson WF]]
[[Category: Bagnoli F]]
[[Category: Bottomley M]]
[[Category: Dubrovska I]]
[[Category: Falugi F]]
[[Category: Filippova E]]
[[Category: Flores K]]
[[Category: Grandi G]]
[[Category: Halavaty A]]
[[Category: Minasov G]]
[[Category: Nocadello S]]
[[Category: Shuvalova L]]