View source for 6bly


==Cryo-EM structure of human CPSF-160-WDR33 complex at 3.36A resolution==
<SX load='6bly' size='340' side='right' viewer='molstar' caption='[[6bly]], [[Resolution|resolution]] 3.36&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6bly]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BLY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6BLY FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.36&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6bly FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bly OCA], [https://pdbe.org/6bly PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6bly RCSB], [https://www.ebi.ac.uk/pdbsum/6bly PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6bly ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CPSF1_HUMAN CPSF1_HUMAN] Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction.<ref>PMID:14749727</ref> 
== References ==
<references/>
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</SX>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Hamilton K]]
[[Category: Sun Y]]
[[Category: Tong L]]
[[Category: Walz T]]
[[Category: Zhang Y]]