View source for 6edj


==Cryo-EM structure of Woodchuck hepatitis virus capsid==
<SX load='6edj' size='340' side='right' viewer='molstar' caption='[[6edj]], [[Resolution|resolution]] 4.52&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6edj]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Woodchuck_hepatitis_virus Woodchuck hepatitis virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6EDJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6EDJ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.52&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6edj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6edj OCA], [https://pdbe.org/6edj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6edj RCSB], [https://www.ebi.ac.uk/pdbsum/6edj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6edj ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/HBEAG_WHV1 HBEAG_WHV1] May regulate immune response to the intracellular capsid in acting as a T-cell tolerogen, by having an immunoregulatory effect which prevents destruction of infected cells by cytotoxic T-cells. This immune regulation may predispose to chronicity during perinatal infections and prevent severe liver injury during adult infections.[HAMAP-Rule:MF_04076]
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</SX>
[[Category: Large Structures]]
[[Category: Woodchuck hepatitis virus]]
[[Category: Wang JC]]
[[Category: Zhao Z]]
[[Category: Zlotnick A]]