View source for 6nrd


==hTRiC-hPFD Class4==
<SX load='6nrd' size='340' side='right' viewer='molstar' caption='[[6nrd]], [[Resolution|resolution]] 8.20&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6nrd]] is a 14 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NRD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6NRD FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 8.2&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6nrd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nrd OCA], [https://pdbe.org/6nrd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6nrd RCSB], [https://www.ebi.ac.uk/pdbsum/6nrd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6nrd ProSAT]</span></td></tr>
</table>
== Disease ==
[https://www.uniprot.org/uniprot/TCPE_HUMAN TCPE_HUMAN] Hereditary sensory and autonomic neuropathy with spastic paraplegia. The disease is caused by mutations affecting the gene represented in this entry.
== Function ==
[https://www.uniprot.org/uniprot/TCPE_HUMAN TCPE_HUMAN] Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin.<ref>PMID:20080638</ref> 

==See Also==
*[[Chaperonin 3D structures|Chaperonin 3D structures]]
== References ==
<references/>
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</SX>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Aebersold R]]
[[Category: Chiu W]]
[[Category: Frydman J]]
[[Category: Gestaut DR]]
[[Category: Joachimiak LA]]
[[Category: Leitner A]]
[[Category: Ma B]]
[[Category: Pintilie G]]
[[Category: Roh SH]]
[[Category: Walzthoeni T]]