View source for 6qtc


==tSH2 domain of transcription elongation factor Spt6 complexed with tyrosine phosphorylated CTD==
<StructureSection load='6qtc' size='340' side='right'caption='[[6qtc]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6qtc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Candida_glabrata Candida glabrata]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QTC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6QTC FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6qtc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qtc OCA], [https://pdbe.org/6qtc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6qtc RCSB], [https://www.ebi.ac.uk/pdbsum/6qtc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6qtc ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SPT6_CANGA SPT6_CANGA] Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression (By similarity).

==See Also==
*[[Elongation factor 3D structures|Elongation factor 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Brazda P]]
[[Category: Krejcikova M]]
[[Category: Kubicek K]]
[[Category: Smirakova E]]
[[Category: Stefl R]]